Key Futures of HMDS:
India is one of the biggest manufacturers of pharma products and is also one of the biggest exporters in the world. The reason why Indian pharma products are popular is the quality and competitive pricing. Since, the demand for the Pharma Intermediates India is very high all over the world many reputed companies in India are involved in manufacturing these products. The most important thing is the purity of the products which is offered by the manufacturers in India.
(HMDS / HMDZ) CAS No. : 999-97-3 is a clear colourless liquid which is a derivative of trimethylsilyl groups and ammonia in place of two hydrogen atoms. It is also known as Hexamethyldisilazane. The molecular formula of this product is C6H18OSi2. It hydrolyses in humid air and therefore there are special techniques to handle it. One of the techniques used to handle it is known as air-free techniques. The boiling temperature of this chemical is in the range of 101° C – 104° C.
How Does HMDS work?
In the non-hydrated surfaces, a chemical bond is created between the Si atom of HMDS and the oxygen of the oxidized surfaces. In this process ammonia is also released. Followed by the methyl group of HMDS breaks and create a hydrophobic surface. This improves rest wetting and adhesion.
Correct Application of HMDS is very important in order to ensure that the resist adhesion does not deteriorate.
Use of (HMDS / HMDZ) CAS No. : 999-97-3
As Hexamethyldisilazane is a specialized organosilicon compound, it is also an important reagent and solvent. These uses make HMDZ an important chemical and therefore it has great demand in the market. It is used to silylate laboratory glassware and turns it hydrophobic. It is also used in gas chromatography to silylate OH groups of organic compounds in order to increase their volatility. This enables GC analysis of the chemicals which are non-volatile. The uses of HMDS are in several fields. It is used in electron microscopy as an alternate to critical point drying at the time of sample preparation.
One of the significant uses of HMDS is reagent in condensation reactions of heterocyclic compounds such as in the microwave synthesis of a derivative of xanthine.Sylilated diagnostic products are prepared at the time of pyrolysis by adding the chemical to the analyte in the process of pyrolysis-gas chromatography-mass spectrometry. This increases the detectability of compounds with polar functional groups. HMDS is also used in the conversion of alcohols into trimethylsilyl ethers.
Being one of the important manufacturers and exporters of Pharma Intermediates India tops the list. In order to get quality ingredients for manufacture of pharmaceuticals in bulk it is essential to depend only on dependable suppliers.